In most cases of pituitary adenomas, surgery can be done for removing it by often using a minimal invasive approach via the nasal cavity and skull base which is called as the trans-nasal, trans-sphenoidal approach. In case of large pituitary adenomas, craniotomy is required where the skull is opened for removing the tumor. Radiotherapy, that includes stereotactic approaches, is performed for the inoperable cases. Even if there are no generally accepted therapeutic managements in case of primary brain tumors, a surgical attempt for removal of the tumor or at least cytoreduction is performed. Cytoreduction is done for removing the brain tumor as much as possible so as to reduce the number of tumor cells that are available for proliferation. This surgery is recommended in most primary brain tumor cases. But, because of the infiltrative characteristics of these lesions, the recurrence of tumor is not quite uncommon, even after undergoing a complete surgical removal.
Radiotherapy and chemotherapy after the operation are important parts of the therapeutic standard in cases of malignant tumors. In cases of “low-grade” gliomas, radiotherapy can also be administered when surgically removal or reduction is not possible. IN primary brain tumors, the survival rates depend on factors like the tumor’s type, patient’s age, his/her functional status, the extent of surgical removal of tumor, etc. Patients suffering from benign gliomas have a survival rate of many years, except in most cases of glioblastoma multiforme that survival rate is just for few months after diagnosis. Surgical removal is the main option of treatment for single metastatic tumors.
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